Electronic Journal of Differential Equations, Vol. 2025 (2025), No. 88, pp. 1-23. Title: Multiple solutions for parametric weighted (p,q)-equations Authors: Xiaohui Zhang (Jiangsu Normal Univ., Xuzhou, Jiangsu, China) Xian Xu (Jiangsu Normal Univ., Xuzhou, Jiangsu, China) Abstract: In this article, we prove that equations driven by a weighted (p,q)-Laplacian have at least two positive solutions, two negative solutions, and two sign-changing solutions. To obtain these result, we construct an operator that has invariant sets consisting of supersolustions and subsolutions. Then using this operator, we find a locally Lipschitz continuous operator and use it to construct a descending flow. Finally, by the method of invariant sets of descending flow, we obtain the 6 solutions stated above. Submitted May 7, 2025. Published September 11, 2025 Math Subject Classifications: 35D30, 35J60, 35J92, 47K10, 58R05. Key Words: Invariant sets with descending flow; multiple solutions; parametric weighted (p,q)-equations.